Methamphetamine is a chiral compound with two enantiomers, dextromethamphetamine and levomethamphetamine. At room temperature, the free base of methamphetamine is a clear and colorless liquid with an odor characteristic of geranium leaves. It is soluble in diethyl ether and ethanol as well as miscible with chloroform. Also Methamphetamine is a potent central nervous system stimulant which affects neurochemical mechanisms responsible for regulating heart rate, body temperature, blood pressure, appetite, attention, mood and responses associated with alertness or alarm conditions.
The acute effects of the drug closely resemble the physiological and psychological effects of an epinephrine-provoked fight-or-flight response, including increased heart rate and blood pressure, vasoconstriction (constriction of the arterial walls), bronchodilation, and hyperglycemia (increased blood sugar). Users experience an increase in focus, increased mental alertness, and the elimination of fatigue, as well as a decrease in appetite. Furthermore It is a member of the amphetamine group of sympathomimetic amines. Also Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. pubchem
IUPAC Name: (2S)-N-methyl-1-phenylpropan-2-amine
Boiling Point: 215.5±9.0 °C at 760 mmHg
Melting Point: 172 °C at 760 mmHg
Density: 0.9±0.1 g/cm3
Appearance: clear crystalline solid
Molecular Weight: 149.237 g/mol
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Can is prepared by reducing ephedrine or pseudoephedrine,.. Preparation of methamphetamine is also by starting from phenylacetone by either the Leuckart or reductive amination methods. In the Leuckart reaction, one equivalent of phenylacetone is in mixture with two equivalents of N-methylformamide to produce the formyl amide of methamphetamine plus carbon dioxide and methylamine as side products. In this reaction, an iminium cation forms as an intermediate which reduction by the second equivalent of N-methylformamide. The intermediate formyl amide is then hydrolyzed under acidic aqueous conditions to yield methamphetamine as the final product. Furthermore Alternatively, phenylacetone can be in mixture with methylamine under reducing conditions to yield methamphetamine
Analysis of illicit preparations of methamphetamine … revealed presence of significant quantities of zinc and minor amount of titantium.