Buy Ergotamine


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Cas Number:       379-79-3

            Purity:         99.12%
Molecular Weight:        581.673 g/mol

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Buy Ergotamine an ergopeptine and part of the ergot family. It is an alpha-1 selective adrenergic agonist and is commonly in use in the treatment of migraine disorders. Also Ergotamine is metabolized by the liver by large pathways, and 90% of the metabolites are come out in the bile.

Ergotamine acts on migraine by one of two proposed mechanisms:

  1. Activation of 5-HT1D receptors on intracranial blood vessels, including those on arterio-venous anastomoses, leads to vasoconstriction, which correlates with the relief of migraine headache.
  2. Also Activation of 5-HT1D receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.IUPAC Name:         (5’α)-5′-Benzyl-12′-hydroxy-2′-methyl-3′,6′,18-trioxoergotamanMolecular Formula:        C33H35N5O5
           Melting Point:          213.5 °C
      Water Solubility:          slidely soluble, 2.23e-01 g/L

Storage: Best at room cool temperatures (25 deg C) and protect from light, moisture.

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