Buy Phenylacetone Online.

Buy Phenylacetone Online.

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What is Phenylacetone?

Phenylacetone is an organic compound with the chemical formula C6H5CH2COCH3. Also it is a colorless oil that is soluble in organic solvents. Furthermore this substance is used in the manufacture of methamphetamine and amphetamine, where it is commonly known as P2P.  Also most popular precursor to amphetamine and methamphetamine is phenyl-2-propanone or Phenylacetone. Also there is an astounding array of synthetic routes to this compound, both due to the relative simple structure of the compound, and also because of its popularity. Finally many of the syntheses can also be tweaked to produce substituted phenyl-2-propanones, such as the ever popular MDMA precursor MDP2P (3,4-methylenedioxyphenyl-2-propanone) by using starting materials with the desirable aromatic substituents.

Synthesis with P2P and Other Reactions

A simple procedure for the synthesis of methamphetamine is reductive amination, reacting phenylacetone with methylamine under reducing conditions. Also any suitable reducing agent could be used, such as sodium borohydride. Therefore this reaction produces racemic methamphetamine, a 50/50 mix of the L and D isomers. However the D isomer has considerably more activity on the central nervous system. Furthermore in order to crystallize the methamphetamine it is then treated with hydrochloric acid to form a salt (methamphetamine hydrochloride). Also a problem with this procedure, however, is that phenylacetone is a controlled substance because of its common use in methamphetamine synthesis. Also it is relatively straight forward to synthesize it independently. Finally with benzene, we simply have to add an acetone substituent.


Phenyl-2-Propanone from Benzyl Cyanide


A solution of sodium ethoxide is prepared from 60 g. (2.6 mol) clean sodium and 700 ml of absolute alcohol (dried over calcium oxide or sodium) in a 2000 ml round-bottomed flask equipped with a reflux condenser. Also to the hot solution added a mixture of 234g (2 moles) of pure benzyl cyanide 264g (3 moles) of dry ethyl acetate (dried by refluxing over P2O5 for 30min followed by distillation). Further stir next morning the mixture with a wooden rod to break lumps, cooled in a freezing mixture to -10°C, and keep at this temperature for two hours.

Then the sodium salt is on a 6 inch Buchner funnel and wash four times on the funnel with 250 ml portions of ether. Thereafter filter cake is practically colorless and corresponds 250-275g of dry sodium salt, or 69-76% of the calculated mount. Furthermore the precipitate separated by suction filtration and wash four times on the funnel with 250 ml portions of water. Also the moist cake weighing about 300g corresponds to 188-206g (59-64%) of dry colorless alpha-phenylacetoacetonitrile, mp 87-89°C.

Phenyl-2-propanone by nitroalkylation of benzene

Titanium Tetrachloride Method7

To a stirred solution of 2-nitropropene (0.1 mol, 8.7g) in dry CH2Cl2 (300ml) was added benzene (0.5 mol, 39g) at room temperature. However the organic phase put separate, the aqueous phase extract with CH2Cl2, and the pooled organic extracts washed with 1 M Na2CO3 solution and dried over MgSO4. Also evaporation of the solvent followed by vacuum distillation (bp 100-101°C at 14mmHg) afforded Phenyl-2-propanone.


Buy 1-Phenyl-2-propanone, Buy 2-Propanone, Buy 1-phenyl-, Buy Phenyl-2-propanone, Buy Methyl benzyl ketone and  Buy Fenproporex-M (desamino-oxo-). Also Buy benzylmethylketon, Buy 1-Phenylpropan-2-one, Buy Phenylaceton and 3-Phenyl-2-propanone. Also Buy a-Phenylacetone, Buy Phenylmethyl methyl ketone, Buy P2P, Buy NSC 9827, Buy 1-PHENYLACETONE and Buy 1-PHENYL-2-PROPANONE. Finally buy BENZYL METHYL KETONE, Buy PHENYLACETON.



1) Phenylacetone

ChemIDplus Chemical Information Classification


2) 2-Propanone, 1-phenyl-







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